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Coreg or Lopressor For Anxiety: Which Should I Take?


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Benzodiazepines like Xanax, Klonopin, or Valium are the first line of treatment for many anxiety disorders. However, benzodiazepines are highly addictive, and their side effects include drowsiness, sedation, confusion, and unsteadiness.

For people with a history of substance abuse or who work a job that requires them to drive frequently, operate heavy machinery, or use fine motor skills, benzodiazepines are not an appropriate choice for anxiety treatment.

If you need an alternative anxiety treatment that specifically addresses the physical symptoms of anxiety, stress, and panic—elevated blood pressure, a racing heart, and heavy sweating—then you’ll want to learn more about beta blockers, including Coreg and Lopressor.

Though primarily prescribed for cardiovascular conditions, beta blockers can effectively treat the physical symptoms of anxiety.

The healthcare providers on Klarity can prescribe beta blockers for anxiety through our online telehealth service. We’ve helped over 30,000 Americans find affordable and accessible depression, anxiety, ADHD, and insomnia medication online. This unique telehealth service helps you get the treatment you need fast and at a low cost. 

All you need to do to speak with a fully-licensed and trained medical provider is take a brief, 2-minute online mental health assessment, and you can get a prescription within 48 hours!

Lopressor and Coreg are the Same Class of Drugs (Beta Blockers)

Two common beta blockers are Coreg and Lopressor. Both work similarly and have similar effects on the body. However, there are subtle differences that this article will outline to help you choose the beta blocker that best suits your medical profile. 

What Are Beta Blockers?

Beta-blockers are a class of medication that was originally developed to treat hypertension (high blood pressure). Since their initial pharmaceutical debut, they’ve been prescribed to treat various cardiovascular issues and other conditions like glaucoma and anxiety.

How Do Beta Blockers Work?

Beta-blockers, as the name implies, block the beta receptors that line the cells in various systems of your body. Specifically, beta blockers block adrenergic receptors, which react to certain hormones such as adrenaline and epinephrine.

Adrenaline and epinephrine are hormones responsible for triggering the fight-or-flight response. When adrenaline or epinephrine enters a beta receptor, it triggers the heart to pump faster and harder, induces sweating, and increases alertness.

The beta receptors that these drugs are designed to block are Beta-1 and Beta-2 receptors. 

Beta-1 Receptors

Beta-1 receptors are found in the heart and kidneys. When activated, they cause blood pressure and heart rate to increase. Also, they cause the heart to pump with more force.

Beta-2 Receptors

Beta-2 receptors are found in smooth muscle systems like blood vessels, the nervous system, and the respiratory system. When activated, Beta-2 receptors increase heart rate and the amount of force the heart uses to pump blood. However, they also cause blood vessels and respiratory muscles to relax.

Lopressor and Coreg Can Treat Physical Symptoms of Anxiety

Essentially, adrenaline gears your body up to react to danger via the fight-or-flight response. Beta-blockers block the receptors that trigger the fight-or-flight response.

People with anxiety disorders often experience physical symptoms associated with the fight-or-flight response—racing heart, hyper-ventilating, increased blood pressure, sweating, and muscle tension, to name a few.

Because beta-blockers suppress the fight-or-flight response, they are often prescribed to treat the physical symptoms of anxiety in people with anxiety disorders.

What Else Does Lopressor Treat?

Like most beta-blockers, Lopressor is primarily used to treat a variety of other cardiovascular conditions, including:

  • Angina (chest pain) 
  • Acute myocardial infarction
  • Congestive heart failure

Off-label Uses for Lopressor  

  • Supraventricular tachycardia (fast heartbeat)
  • Arrhythmia (irregular heartbeat)
  • Thyrotoxic crisis (thyroid storm)
  • Managing the physical symptoms of anxiety

What Else Does Coreg Treat?

Coreg has a similar treatment profile to Lopressor. It treats the same cardiovascular symptoms as Lopressor and has a similar off-label treatment profile.

Coreg and Lopressor Are Not First-Line Hypertension Treatments 

Both Coreg and Lopressor are no longer first-line treatments for hypertension. This is because other beta blockers perform that specific cardiovascular function better than Coreg or Lopressor. However, Coreg and Lopressor are first-line treatments for heart attacks, congestive heart failure, and chest pain. 

Doses, Dosage Form, and Side Effects of Coreg 

Common Coreg Doses and Forms

Coreg comes in a variety of forms and doses. The type and potency of Coreg depend on what condition it is treating.

Coreg extended-release capsules come in the following doses:

  • 10mg
  • 20mg
  • 40mg
  • 80mg

Coreg immediate-release tablets come in the following doses:

  • 3.125mg
  • 6.25mg
  • 12.5mg
  • 25mg

Healthcare providers recommend taking Coreg with food twice a day. Patients who skip a dose can experience a dramatic blood pressure spike, increasing the chances of heart attack or stroke. 

Common Coreg Side Effects

Common side effects of Coreg include:

  • Dizziness
  • Bradycardia (slow heart rate)
  • Postural Hypotension (drop in blood pressure when standing from sitting or when sitting up from lying down)
  • Insomnia
  • Diarrhea 

Coreg Drug Warnings

Suddenly stopping Coreg can dramatically increase blood pressure, increasing the likelihood of heart attack and stroke.

People with severe COPD or Asthma should not take Coreg. However, patients with mild asthma or COPD can take Coreg if medically supervised and cleared. 

Taking Coreg will reduce high blood pressure and reduce how fast and hard the heart works. Certain symptoms of other diseases, like hyperthyroidism and diabetes, include high blood pressure and a racing heart. 

As a result, Coreg can mask the onset of hypoglycemia (low blood sugar) and symptoms of hyperthyroidism. If you have diabetes or hyperthyroidism, make sure to test/monitor regularly in case Coreg is masking symptoms of those other conditions. 

Common Coreg Drug Interactions

Taking Coreg with heart rhythm drugs can cause adverse reactions, such as worsening a heart blockage or lowering blood pressure to dangerous levels. Examples of heart rhythm medication include:

  • Sotalol
  • Disopyramide
  • Encainide
  • Flecainide
  • Amiodarone
  • Bretylium
  • Quinidine
  • Digoxin
  • Propafenone
  • Procainamide

Coreg should not be used with other beta-blockers, as the effects of each drug will be more severe. Common beta-blockers (besides Lopressor and Coreg) include:

  • Inderal or Angilol (propranolol)
  • Sotalol
  • Tenormin (atenolol)
  • Cardicor or Emcor (bisoprolol)
  • Trandate (labetalol)

Taking Coreg with non-beta-blocker blood pressure medication, such as clonidine, can cause an unsafe drop in blood pressure. Your medical provider should monitor you for drastic drops in blood pressure.

Taking Coreg with calcium-channel blockers can also lead to unsafe drops in blood pressure and the development of arrhythmia. Common calcium channel blockers include diltiazem

and verapamil.

Taking Coreg with diabetes medication can cause blood sugar levels to drop to unsafe levels. Coreg can also mask certain diabetes symptoms. People with diabetes who take Coreg need to monitor blood sugar levels more frequently than people with diabetes who do not take Coreg. 

Coreg can also interact with transplant rejection drugs. Taking Coreg while also taking cyclosporine can elevate levels of cyclosporine. Patients need to be monitored and have the dose of their transplant rejection medication modified when taking Coreg. 

How Much Does Coreg Cost?

The price of Coreg depends on several factors, including your health care coverage, the location of your pharmacy, and whether you get generic or name-brand Coreg. Generally, a 30-day supply (60 tablets) of 25 mg Coreg tablets costs between $7 and $36.

Doses, Dosage Form, and Side Effects of Lopressor   

Common Lopressor Doses and Forms

Lopressor comes in a variety of forms, including tablets, capsules, and an injectable solution. It also has several brand names depending on what it’s being prescribed to treat. 

Lopressor is available in a solution strength of 1mg/mL as an injectable solution.

As an immediate-release tablet, Lopressor is available in the following doses. Note the brand name Lopressor is only available for some of the following doses. Because it is an immediate-release table, patients must take Lopressor with food.

  • 25mg in generic form
  • 50mg in generic form and available as Lopressor
  • 100mg in generic form and available as Lopressor

In extended-release form, the medication is called Toprol XL. It only needs to be taken once per day instead of twice daily.

  • 25mg
  • 50mg
  • 100mg
  • 200mg

Common Lopressor Side Effects

Lopressor has a similar side effect profile to Coreg. However, there are several differences between the two that readers need to be aware of. Lopressor can cause depression, shortness of breath, and tiredness, which are not widely reported in users of Coreg. 

Other side effects of Lopressor include:

  • Skin Rash
  • Depression
  • Shortness of Breath/Wheezing
  • Slowed Heart Rate
  • Tiredness
  • Dizziness
  • Diarrhea
  • Itchiness

Lopressor Drug Warnings

Lopressor has many of the same drug warnings that Coreg has. Here are the drug warnings again in brief.

Suddenly stopping beta-blockers like Lopressor or Coreg can cause a severe spike in blood pressure, which increases the likelihood of a stroke or heart attack.

People with severe COPD or Asthma should not take Lopressor. Patients with mild asthma or COPD can take Lopressor if monitored closely for respiratory symptoms and cleared by a healthcare provider to take the medication.

Taking beta-blockers like Coreg or Lopressor can mask symptoms of hyperthyroidism and diabetes. People with these conditions must monitor themselves for hyperthyroidism and frequently test for low blood sugar levels. 

Common Lopressor Drug Interactions

Lopressor should not be taken with other blood pressure or heart medication without approval from a healthcare provider. Common blood pressure medications include beta-blockers, like:

  • Coreg
  • Inderal or Angilol (propranolol)
  • Sotalol
  • Tenormin (atenolol)
  • Cardicor or Emcor (bisoprolol)
  • Trandate (labetalol)

And calcium channel blockers, like:

  • Diltiazem
  • Verapamil

Lopressor should not be taken with certain antidepressant medications without approval from a healthcare provider.

  • Wellbutrin
  • Prozac 
  • Paxil
  • Clonidine
  • Thioridazine

How Much Does Lopressor Cost?

The price of Lopressor varies depending on your health coverage, the location of your pharmacy, and the form/dose you need for treatment. However, for a 30-day supply (60 tablets) of generic Lopressor (called Metoprolol), prices range between $3.50 and $15.

Do I Need A Prescription for Lopressor or Coreg?

Yes, you will need a prescription to take Lopressor or Coreg. Due to the potential side effects of beta-blockers, healthcare providers only prescribe these medications after carefully considering your general health, medical needs, medical profile, and medical history.

Coreg and Lopressor Frequently Asked Questions

Here are some questions Klarity frequently receives. If you have questions about Coreg, Lopressor, or beta-blockers in general, chances are we have answered them below! 

What is Coreg?

Coreg, or Carvedilol (generic), is a beta-blocker prescribed to manage various cardiovascular issues and other health conditions, such as glaucoma and anxiety. 

What is Lopressor?

Like Coreg, Lopressor (Metoprolol) is another beta-blocker that works similarly to Coreg. It also treats various cardiovascular conditions, glaucoma, and anxiety. 

Are Coreg, Lopressor, and other Beta Blockers the same drug?

Though they are chemically very similar, Coreg and Lopressor have chemical and structural differences. These slight differences lead to slightly different side effect profiles for each medication. However, they are still quite similar. 

What’s better for anxiety? Coreg or Lopressor?

Both Coreg and Lopressor are effective at treating the physical symptoms of anxiety. However, readers must know that they do not address the underlying causes of anxiety disorders. 

Regarding determining which medicine is better, readers should compare the side effect profile for each medication, consult with a medical provider, and decide which one seems best for their particular medical profile. 

Can I breastfeed on Coreg or Lopressor?

Lopressor is considered safe to take while breastfeeding. There aren’t enough studies available to effectively determine if Coreg is safe to take while breastfeeding, though the current consensus—based on existing studies—is that breastfeeding on Coreg presents little to no risk to the infant. 

Can I drink alcohol on Coreg or Lopressor?

Drinking alcohol causes an initial spike in blood pressure, followed by a gradual decrease. Because alcohol affects blood pressure in this way, healthcare providers advise not drinking while taking beta-blockers, which also lower blood pressure. 

Does it matter what time of day I take Coreg or Lopressor?

If taking beta-blockers for cardiovascular conditions, you’ll have to take them twice a day with food. However, if taking beta-blockers to treat the physical symptoms of anxiety, your dosing schedule might vary. 

Because dizziness and drowsiness can occur after taking beta-blockers, your medical provider may suggest taking beta-blockers for anxiety before bed. 

Klarity Will Help You Find Effective, Non-Habit-Forming Anxiety Medication Alternatives Online

If you can’t take benzodiazepines because of the nature of your work or because of your medical history, Klarity can help you find non-relaxant anxiety medication—all without having to wait months to receive it!  

Klarity has helped 30,000 people find affordable and effective online anxiety, depression, ADHD, and insomnia medication through our novel telemedicine services. Start your non-relaxant anxiety treatment in as little as 48 hours.

We’ll put you in contact with an anxiety specialist who can diagnose and prescribe anxiety medication online. They will help you choose the best medication and send your prescription to your local pharmacy for pick-up at your convenience.

Start today, and discuss your symptoms with a specialist who can help.

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