Why wait to prioritize your mental health? Get started toward a happier, healthier life on Klarity now.
Depression
22 min read
Written by Klarity Editorial Team
Published: Oct 28, 2022
Medically Reviewed by Dr. Zoe Russell
It’s a common misperception that ADHD is only a children’s disease. Though commonly diagnosed in school-aged children, not all ADHD symptoms go away when those children grow into adults.
Sometimes, a person won’t develop ADHD symptoms until after they reach adulthood. Other times, children with the disorder grow up without a diagnosis and only realize they have ADHD after being treated for a different mental illness.
All told, a conservative estimate places the percentage of adults with ADHD at 4.4%. Out of this population, only roughly 20% have sought treatment for ADHD symptoms. It follows that a large majority—80%—of adults with ADHD do not seek treatment for ADHD but may be seeking treatment for comorbid depression and anxiety.
However, their depression and anxiety might be caused by untreated ADHD.
In cases like this, treating ADHD is crucial for addressing comorbid anxiety and depression.
Mental health can be complicated. If you suspect your comorbid depression and anxiety disorders might be caused by untreated adult ADHD, you’ll need mental health specialists to help you receive a proper diagnosis and treatment.
Klarity makes it easy to connect with board-certified mental health providers in your state who can diagnose and prescribe treatments for depression, anxiety, and adult ADHD.
Meet your board-certified mental health provider today.
Comorbidity is the presence of two or more illnesses in the same patient. ADHD, depression, and anxiety can all be comorbid with one another. However, the presence of two or more of these mental illnesses in one person complicates the relationship between anxiety, depression, and ADHD and makes developing the most effective treatment plan more challenging—
—Do you treat ADHD to alleviate anxiety and depression symptoms? Or do you treat depression symptoms to help people manage their comorbid illnesses? Or both?
Those are the questions this post will address.
In truth, there are several ways ADHD, depression, and anxiety can manifest in a patient. Anxiety and depression can exist independently of ADHD, or they can develop due to the stress and challenges of living with untreated ADHD.
ADHD is a highly heritable genetic condition. Likewise, there is evidence that both depression and anxiety are heritable. A person with ADHD is three times more likely to develop depression than the general population. Clearly, ADHD symptoms overlap heavily with symptoms of anxiety and depression.
This makes it more complicated for psychologists and other mental health professionals to discover the underlying causes of symptoms, which is a crucial part of formulating the most effective treatment plan.
First, let’s review the most common symptoms of ADHD, depression, and anxiety. In the following lists, overlapping symptoms will be in bold.
Symptoms of attention deficit hyperactivity disorder are divided into two categories:
A person with attention deficit hyperactivity disorder might only have inattentive symptoms and not have hyperactive or impulsive symptoms or vice versa. Sometimes, they could have both. Both symptoms are common in children, but hyperactive and impulsive symptoms don’t always carry over into adulthood.
It’s important to note the difference between primary and secondary depression. With primary depression, the symptoms are most likely inherited and don’t have clear circumstantial causes. This contrasts with secondary depression, which has a clear cause—another mental or physical illness (chronic or terminal illness), life circumstances, or past trauma.
Whether depression is primary or secondary, the symptoms are often the same. Remember, overlapping symptoms between anxiety, depression, and attention deficit hyperactivity disorder are in bold:
Several disorders fall under the umbrella category of “anxiety disorders.” General anxiety disorder (GAD), panic disorder (PD), social anxiety disorder, and various phobias are included.
For this post, the focus will be on the symptoms of generalized anxiety disorder, which include:
People with all three conditions (or some combination of all three conditions) may experience difficulty focusing, concentrating, and paying attention. They may appear restless or otherwise agitated and get distracted easily.
This symptomatic overlap provides some insight into the links between depression, anxiety, and adult ADHD. But we’ll need to explore a few things in greater detail to see the full picture.
We’ll look at the following:
Dopamine is one of many neurotransmitters (or chemical messengers) that brain cells use to communicate with one another and with other parts of the body. Specifically, dopamine helps regulate (or is in part responsible for):
Dopamine is also critical for creating norepinephrine and epinephrine, which are vital to memory, alertness, learning, and attention in the brain and central nervous system.
Studies have shown that low levels of dopamine in certain areas of the brain can lead to problems with motivation, attention, and a lack of desire to do pleasurable or joyful activities (due to dopamine’s role in regulating the brain’s reward center).
However, when dopamine levels are too high, it can lead to aggressiveness and impulsiveness. Therefore, the current research indicates that imbalanced dopamine levels in certain brain areas can cause some symptoms of anxiety, depression, and ADHD.
Below are three ways undiagnosed ADHD can cause adults to develop secondary depression and anxiety.
Untreated ADHD can lead a person to develop secondary depression, an anxiety disorder, or both. When untreated, a person with ADHD has difficulty succeeding in school, work, and interpersonal relationships. They might make impulsive decisions like gambling, overspending, and misusing drugs and alcohol.
A person who doesn’t realize they have ADHD might blame themselves for the poor circumstances they find themselves in. They might develop depression or anxiety because they don’t understand why it is so difficult for them to accomplish tasks that they see others completing with ease.
Because their ADHD is untreated, they’ll have poor self-esteem and are at a greater risk of developing anxiety and depression.
A key symptom of ADHD, anxiety, and depression is emotional dysregulation. People with difficulty controlling or regulating their emotional responses to various stimuli might grow angry, irritated, and frustrated at seemingly small or insignificant things.
When any mental illness is untreated, symptoms like emotional dysregulation can make maintaining relationships with others difficult, as the person might appear disproportionately angry, irritable, or frustrated.
When others who make up that person’s support group are pushed away, it causes more isolation for the person with the mental illness, further exacerbating depressive or anxious symptoms.
If the underlying cause of emotional dysregulation comes from primary depression or anxiety, which are more often diagnosed in adults when compared to ADHD, then treating the depression or anxiety through standard means (antidepressants and psychotherapy) will help reduce symptoms.
However, if the underlying cause of emotional dysregulation is undiagnosed ADHD, antidepressants might only address the secondary depression but not treat the root problem.
Low motivation and poor concentration are shared symptoms across ADHD, anxiety, and depression. Dopamine imbalance in the brain is associated with all three mental illnesses. As mentioned earlier, dopamine is a key neurotransmitter that regulates attention, concentration, learning, and motivation.
Most antidepressants and CNS stimulants have a measurable effect on the levels of dopamine or dopamine-dependent chemicals in the brain.
Antidepressants (Paxil, Prozac, Zoloft, etc.):
CNS Stimulants (Adderal, Vyvanse, Concerta, Focalin, etc.):
CNS stimulants increase catecholamine levels in the brain. Both norepinephrine and dopamine belong to the catecholamine chemical group.
When people get ADHD treatment and experience relief from ADHD symptoms, they can make better, less impulsive decisions, stay on task and organized at work or school, and focus on bettering themselves.
If ADHD symptoms are causing secondary depression and anxiety, treating them accordingly helps reduce the risk of developing secondary depression and anxiety.
Yes, undiagnosed and untreated ADHD can cause secondary depression and anxiety symptoms. If you fail to get work done on time, constantly miss appointments, make risky, impulsive decisions, and lose important items, your self-esteem might start to suffer—especially if you compare yourself to others who do not seem to have the same issues.
Plus, if other people chastise and demean you for these things, it will only further reinforce your low self-esteem. This negative feedback loop can cause a person to develop depression and anxiety disorders.
But what’s the fix, then?
Do you treat depression or anxiety before treating ADHD? Do you treat ADHD first? Can you treat both at the same time?
The usual course of action is treating the condition causing the most immediate harm. If a person’s secondary depression has gotten so bad that they are suicidal, medical professionals will prioritize treating the depression over other conditions.
However, if depression and anxiety symptoms are less severe, a medical professional might recommend treating ADHD with medication and seeing how that affects the symptoms. Additionally, it is possible to treat all three simultaneously with a combination of stimulants and antidepressants.
When treating multiple disorders at once, medical professionals must be careful in prescribing medication. As mentioned above, many of these conditions result from imbalances where there is too much or too little of a certain neurotransmitter in different parts of the brain.
Because of all the variables—including a person’s unique body chemistry—finding the right mix of medications requires trial and error. However, there are some promising synergies between certain medicines.
Stimulants can be prescribed off-label alongside traditional antidepressants for treatment-resistant depression. This combination is considered safe. However, there is an increased risk of developing serotonin syndrome.
Serotonin syndrome is a condition in which too much serotonin builds up in the brain, causing
Though rare, it can be fatal. Serotonin syndrome usually occurs within the first few hours of taking a new medication that increases serotonin levels, changing your dose, or adding a serotonin-elevating drug to your current list of medications.
Antidepressants that primarily affect norepinephrine and dopamine can help alleviate ADHD and anxiety symptoms. Medical providers may suggest an antidepressant for ADHD if the person cannot take stimulants because of a heart condition or drug dependency issues.
Antidepressants that elevate norepinephrine and dopamine include
The classification of medications for anxiety, depression, and ADHD as controlled substances varies depending on the specific medication and its potential for abuse or misuse.
As a general overview, commonly prescribed controlled substances include:
Antidepressants are less likely to fall under the category of controlled substances, but be sure to check with your healthcare provider about the specific drug you’ve been prescribed and its controlled substance status.
Controlled substances carry a risk of dependence if misused or taken in higher amounts than recommended. For safe and responsible use, it’s essential to take these medications exactly as prescribed, carefully following recommended dosage guidelines.
If you have any questions or concerns, be sure to reach out to your healthcare provider as soon as possible. They can help address your specific needs while minimizing the risk of dependency.
Adults with mental health conditions such as ADHD (Attention Deficit Hyperactivity Disorder), depression, and anxiety may be at an increased risk of developing substance abuse disorders. Several factors may contribute to this increased risk:
Finding the right treatment plan seems like an overwhelming challenge if you have comorbid depression, anxiety, and ADHD. However, you aren’t alone in searching for convenient and fast online treatments.
On Klarity, appointments are always available within 48 hours, so you never have to wait months for treatment when you need it now. Find a provider today to get started.
Sources
“Adult ADHD (Attention Deficit Hyperactive Disorder).” Anxiety and Depression Association of America. https://adaa.org/understanding-anxiety/related-illnesses/other-related-conditions/adult-adhd
“Anxiety Disorders.” National Institute of Mental Health. https://www.nimh.nih.gov/health/topics/anxiety-disorders
Biederman J, Faraone SV, et al. “Evidence of familial association between attention deficit disorder and major affective disorders.” Arch Gen Psychiatry. 1991;48:633–642.
Eileen Bailey. “The Risk of Mixing Stimulant Medication and Antidepressants.” Health Central. https://www.healthcentral.com/article/combining-stimulant-medication-and-antidepressants-possible-interactions
JAMA and Archives Journals. “ADHD Appears To Be Associated With Depressed Dopamine Activity In The Brain.” ScienceDaily. www.sciencedaily.com/releases/2007/08/070806164505.htm
Joel Nigg. “How ADHD Amplifies Emotions.” ADDitude. https://www.additudemag.com/emotional-dysregulation-adhd-video/
Kessler RC, Adler L, et al. “The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication.’ Am J Psychiatry. 2006 Apr;163(4):716-23. doi: 10.1176/ajp.2006.163.4.716. PMID: 16585449; PMCID: PMC2859678.
Lauren Hellicar. “What are the best medications for depression, anxiety, and ADHD?” Medical News Today. https://www.medicalnewstoday.com/articles/best-medication-for-anxiety-depression-and-adhd
Markham Heid. “Antidepressants for Adult ADHD.” WebMD. https://www.webmd.com/add-adhd/antidepressants-adult-adhd
Matt Smith. “The Link Between Depression and ADHD.” WebMD. https://www.webmd.com/add-adhd/depression-adhd-link.
Mayo Clinic Staff. “Depression (Major Depressive Disorder).” Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/depression/symptoms-causes/syc-20356007
Pauline Belujon and Anthony A Grace. “Dopamine System Dysregulation in Major Depressive Disorders.” National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716179/
Roberto Olivardia, Ph.D. “Anxiety? Depression? Or ADHD? It Could Be All Three.” ADDitude. https://www.additudemag.com/adhd-anxiety-depression-the-diagnosis-puzzle-of-related-conditions/.
“Symptoms: Attention Deficit Hyperactivity Disorder.” National Health Service. https://www.nhs.uk/conditions/attention-deficit-hyperactivity-disorder-adhd/symptoms/
Valencia Higuera. “Is there a link between ADHD and depression?” Medical News Today. https://www.medicalnewstoday.com/articles/314905.
Subscribe to our blog for the latest health insights and updates
Join our community of health-conscious individuals and gain access to valuable tips, expert advice, and the newest trends in healthcare.