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Viibryd vs Luvox


Viibryd vs Luvox

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Do you think an SSRI would help your depression or anxiety but aren’t sure which one to try? Choosing the right one can be challenging, especially since they all have similar effects on the body and mind. This comparison guide shows the similarities and differences between two popular SSRI medications—Viibryd and Luvox—to help you choose the best depression treatment. 

All SSRIs require a prescription from a healthcare provider, such as those on Klarity. After you book your first appointment, we’ll connect you with a certified medical professional who can evaluate your condition, recommend and prescribe medication, and schedule regular follow-up appointments. All depression treatment with Klarity takes place 100% online, so it’s always accessible. Take our 2-minute self-evaluation to get started today.

This article discusses suicide, suicidal ideation, and self-harm. If you or someone you know is experiencing suicidal thoughts or is in crisis, contact the Suicide Prevention Lifeline immediately at 800-273-8255.

What is Viibryd?

Viibryd is the brand name for the SSRI medication vilazodone, a well-known selective serotonin reuptake inhibitor (SSRI). SSRIs help regulate brain chemistry by stopping receptors in the brain from taking in serotonin. This process allows more serotonin to stay in the brain, which helps regulate the following: 

  • Mood 
  • Energy levels
  • Appetite
  • Sleep cycles

Common Doses and Forms of Viibryd

Viibryd comes in oval tablets printed with the dosage on one side. They’re also color-coded by dosage, as follows: 

  • 10mg red
  • 20mg yellow
  • 40mg blue

Most individuals start Viibryd by taking 10mg daily and gradually increasing their dosage to the maximum dosage of 40mg daily. Viibryd should be taken with food. 

Conditions Viibryd Treats

Viibryd is only FDA-approved to treat depression. However, it’s often prescribed off-label to treat anxiety and anxiety-related disorders and conditions. 

Viibryd Can Treat Symptoms of Anxiety and Depression

Bringing brain chemistry into balance is one of the most effective ways to treat depression and anxiety. Low serotonin levels can cause opposing symptoms, such as:

  • Extreme fatigue or manic nervousness
  • Apathy or panic attacks
  • Listlessness or insomnia
  • Disinterest in food or nervous nausea

Each set of symptoms can result from depression and/or anxiety. Raising serotonin levels in the brain helps reset its natural rhythms and reactions to alleviate these symptoms. 

Off-Label Uses for Viibryd

Off-label refers to the practice of prescribing medications to treat conditions not approved by the FDA. These medications are considered safe to take; they just haven’t gone through the FDA approval process for every condition they’re able to treat.

For instance, Viibryd is often prescribed off-label for the following: 

  • Obsessive-compulsive disorder
  • Generalized anxiety disorder 
  • Panic disorder

Viibryd Costs

Brand name Viibryd costs much more than generic vilazodone. They’re the same medication with different branding, so it’s more cost-effective to ask for the generic prescription. 

For instance, 30 days’ worth of Viibryd can cost over $340, while the same amount of vilazodone costs around $15. 

Viibryd Side Effects

Viibryd has fewer side effects than most other SSRIs, meaning many patients tolerate it better than other drugs in the same class. Some of its common side effects include: 

  • Nausea
  • Vomiting
  • Diarrhea
  • Insomnia
  • Sexual dysfunction

Less common, more serious side effects may arise if you develop a condition called serotonin syndrome, which is potentially fatal. This condition occurs when your brain is overloaded with serotonin. If you experience any of the following symptoms, seek medical attention immediately: 

  • Seizures
  • Blurred or tunnel vision
  • Eye pain, swelling, or seeing halos around lights
  • Easy bruising or unusual bleeding
  • Racing thoughts or unusual risk-taking behavior
  • Decreased inhibitions, euphoria, or extreme sadness
  • Headache or severe weakness
  • Confusion or slurred speech
  • Loss of coordination or feeling unsteady

Viibryd Warnings

People with certain conditions should not take Viibryd because it could make those conditions worse or interact with the medications used to treat them. These conditions include: 

  • Liver or kidney disease
  • Bleeding or blood clotting disorders
  • Narrow-angle glaucoma
  • Epilepsy
  • Bipolar disorder
  • Sexual function issues
  • A history of drug addiction
  • Suicidal thoughts

Viibryd Drug Interactions

Some medications may interact poorly with each other and cause serious health problems. Those who take the following medications should avoid taking Viibryd: 

  • Monoamine oxidase inhibitors (MAOIs)
  • Pimozide or other Tourettes syndrome medications
  • Thioridazine or other antipsychotic medications
  • Stimulant medications, like Adderall
  • Opioid-based painkillers
  • Herbal supplements, such as St. John’s Wort
  • Tryptophan

What is Luvox?

Luvox is the brand name for an SSRI medication called fluvoxamine. Similar to Viibryd, Luvox boosts serotonin levels in the brain by preventing certain receptors from transferring it to the bloodstream. This process helps relieve the symptoms of depression, anxiety, and other conditions related to mood and brain chemistry.  

Common Doses and Forms of Luvox 

Both brand name Luvox and generic fluvoxamine are white tablets that come in a blister pack. Brand name Luvox tablets are oval, while fluvoxamine is round. Each kind is available in the following dosages: 

  • 25mg
  • 50mg
  • 100mg

Adults over 18 typically start on a 50mg dose and increase it over several weeks up to 300mg per day. 

Conditions Luvox Treats

Luvox is effective for treating an array of conditions related to depression and anxiety. It’s only FDA-approved to treat depression and obsessive-compulsive disorder (OCD) but has several off-label uses. 

Luvox Can Treat Symptoms of OCD and Depression

Though depression and OCD may sometimes be exacerbated by stressful environments or events, SSRIs like Luvox can help alleviate symptoms of these disorders by regulating serotonin production. 

Symptoms of OCD include: 

  • Intense, unreasonable fear
  • Racing and intrusive thoughts
  • Difficulty tolerating uncertainty
  • Requiring order and symmetry to feel safe

Symptoms of depression include: 

  • Extreme fatigue
  • Apathy or listlessness
  • Loss of appetite
  • Insomnia
  • Lack of interest

Off Label Uses for Luvox

Because it’s effective in treating OCD, Luvox is often prescribed off-label for other anxiety-related conditions, including: 

  • General anxiety 
  • Panic disorder
  • Social phobias
  • Eating disorders
  • Borderline personality disorder (BPD)

Luvox Costs

Pricing for brand name Luvox varies from $32 to over $400 for a month’s supply. The generic version, fluvoxamine, costs between $25 and $30 for the same amount. 

Luvox Side Effects

Luvox has more side effects than Viibryd. However, many are mild and may dissipate after a few weeks. Some of the most common side effects include: 

  • Feeling dizzy, weak, sleepy, or tired
  • Constipation, stomach pain, nausea, vomiting, diarrhea, or reduced appetite
  • Dry mouth or change in taste
  • Insomnia
  • Headache or shakiness
  • Excess gassiness
  • Feeling nervous and easily startled
  • Excessive sweating
  • Common cold symptoms

The following symptoms may indicate an allergic reaction to Luvox or other serious health complications: 

  • Allergic reaction, including hives; swelling of the face, mouth, and throat; difficulty breathing
  • Signs of low sodium, including headache, brain fog, weakness, seizures, or trouble balancing
  • Coughing up or vomiting blood; blood in the urine or stool; unusual vaginal bleeding; bleeding that cannot be easily stopped
  • Abnormal weight gain or loss
  • Difficulty passing urine
  • Sexual problems, such as difficulty orgasming or lowered sex drive
    • Erection lasting more than 4 hours
  • Unusual menstrual flow

Like Viibryd, Luvox may also cause serotonin syndrome. If you experience the symptoms of this syndrome listed above, seek medical attention immediately. 

Luvox Warnings

Luvox and other SSRIs may cause adverse reactions in those with the following conditions: 

  • Bipolar disorder
  • Bleeding problems
  • Depression
  • Glaucoma
  • Heart attack or heart disease
  • Heart rhythm problems
  • Hyponatremia (low sodium in the blood)
  • Mania (feeling elated)
  • Seizures
  • Liver disease
  • Habitual tobacco use

Luvox Drug Interactions

Adverse drug interactions can cause serious health complications. If you take any of the following medications, you should consider alternatives to Luvox: 

  • Monoamine oxidase inhibitors (MAOIs)
  • Tourette’s syndrome medications, like pimozide
  • Warfarin and other blood thinners
  • Ibuprofen and other NSAIDs
  • St. John’s Wort 
  • Tryptophan
  • Other SSRIs and antidepressants
  • Stimulant medications like Adderall
  • Certain pain or migraine medications

Get Anxiety and Depression Treatment With Klarity

When you have a mental health condition, you should be focused on managing your symptoms, not struggling to make an appointment. That’s why Klarity is committed to doing it better. 

We allow you to attend appointments from wherever you are. With us, there are no lengthy waiting periods or a need to rearrange your schedule. We can connect you with a healthcare provider in just 48 hours, and—best of all—we don’t use insurance

Do you want comprehensive mental healthcare at your fingertips? Book an appointment today to get started with depression treatment.

Frequently Asked Questions About Viibryd and Luvox

Does Viibryd Make You Gain Weight? Does Luvox?

Neither Viibryd nor Luvox typically causes weight gain. However, if your appetite returns because you’re taking one of these medications, eating more regularly could cause some weight gain. 

Is Viibryd or Luvox Better for Anxiety?

Viibryd is more commonly prescribed to treat anxiety because it’s better tolerated than many other SSRIs and significantly alleviates symptoms. However, Luvox is FDA-approved to treat OCD, an anxiety-related condition, so it could also be effective in treating anxiety. 

Can I Replace Viibryd with Luvox?

Yes, you can replace Viibryd with Luvox provided you do so under medical supervision. Your healthcare provider will either taper you off Viibryd completely and replace it with a low dose of Luvox or taper you off Viibryd while simultaneously taking low doses of Luvox. After the Viibryd is out of your system, you’ll gradually increase your dose until you reach the recommended amount.

Is Viibryd Energizing or Sedating? What About Luvox?

Both medications may cause daytime drowsiness. However, other changes in energy levels depend on why you’re taking the medication. Those taking an SSRI for depression may feel energized, while those taking it for OCD or panic disorder will probably feel calmer and more relaxed.

Does Viibryd Cause Brain Fog? Does Luvox?

The risk of daytime sleepiness and fatigue may cause mild brain fog. However, sudden onset or worsening brain fog may be a serious side effect that requires immediate medical attention. 

Can I Drink Alcohol On Viibryd? On Luvox?

No it’s never safe to drink alcohol while taking an SSRI. Alcohol enhances the medication’s effects, posing very serious health risks. 

Can I Drink Caffeine When I’m on Viibryd? How About Luvox?

Yes, caffeine doesn’t interact adversely with SSRIs, so you can enjoy caffeinated coffee, tea, and other beverages. However, limiting your intake could help the medication work better if you’re taking one of these medications for anxiety.

What Is Better For Depression—Viibryd or Luvox?

Viibryd and Luvox are both FDA-approved to treat depression, and they work the same way in the body to reduce symptoms. Their effectiveness on factors, including: 

  • Other medical conditions you have
  • Other medications you’re taking
  • How well you tolerate each SSRI

If you’re uncertain which one to try first, your healthcare provider on Klarity can evaluate you and make a recommendation.  


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